CHARLOTTE, N.C. (AP) — United Methodist delegates on Thursday removed a 52-year-old declaration from their official social teachings that deemed “the practice of homosexuality ... incompatible with Christian teaching” — part of a wider series of historic reversals of the denomination’s longstanding disapproval of LGBTQ activity.

The historic vote came as delegates also approved a new definition of marriage as a covenant between “two people of faith” while recognizing the couple may or may not involve a man and a woman. That replaces an exclusively heterosexual definition of marriage and followed a debate that exposed tensions between some U.S. and international delegates.

The 523-161 vote to approve a section of the church’s Revised Social Principles took place at the General Conference of the United Methodist Church in the penultimate day of their 11-day legislative gathering in Charlotte.